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Can House (Hugh Laurie) and Cuddy (Lisa Edelstein) really make a relationship between the two of them work? ET is on the set for the new season of the hit FOX doctor drama, premiering Monday night, when House and Cuddy call in sick!

The couple, who in the last season finale admitted they had feelings for each other, goes on a double date with Wilson (Robert Sean Leonard) and his ex-wife Sam (Cynthia Watros) to an indoor Go Kart race track — and ET is there for all the action.

“I think House is trying to struggle with what he and Cuddy have in common, so he is desperately trying to find things that they’ll both enjoy,” Edelstein tells ET. “Sam and Wilson have come along. Sam is definitely on the House team of this-is-the-greatest-thing-she has-done-in-a-long-time. Wilson is more on the Cuddy team of this-could-be-a-big problem.”

Cuddy is just coming off of a breakup, and House, well, House is House and he doesn’t know how to have a successful relationship.

“The thing of it is, is House is trying too hard,” Laurie tells ET. “He’s trying too hard on the race track and he’s trying too hard to make [the relationship] work and to give it long life, because what he fearsĀ the truth is, what he fears is happiness. He convinces himself that happiness is something that has to be built out of things like this [points around him] when in actual fact — I’m not the first to point this out — happiness comes from within.”

Many series are considered to have “jumped the shark” when the two characters who have been flirting with each other for a very long time finally get together. Is that going to be the case on “House”?

“This is not a character who is going to find happiness easily, if ever,” Laurie says. “It is sort of doomed. He gives it a good run. I mean, his commitment is genuine and total. He is a bright man who can apply himself to all kinds of problems. He applies himself to a relationship as if it’s a scientific problem and he gives it everything but it is ultimately doomed.”

“House” premieres tonight at 8 p.m. on FOX.